ECG Plotter


Enter a list of SNPs (rs572474770, rs776293589, 2:179698596), a region (2:179381323-179405807) or a Gene (e.g. SCN5A) and click the Go button to extract variants.


under development, n.verweij@umcg.nl. 2019

(note: Microsoft browsers may not work, try disabling bitdefender)

Colors indicate LD (r2); filled circles indicate the significance of the lead ECG trait; hollow circles indicate the minimum value across ECG all traits.


                  

Please limit to <150 for now, else it will probably fail to plot due to memory issues.

Interactive t-SNE plot (manuscript)


ECG-wide Mendelian randomization

Provide a summary statistics file with up to 1000 variants. Include the following columns with headers: CHR, BP, EFAL, NEFAL, EAF, BETA, SE. Ensure positions are on Build 37. This is a try-out. It may be very slow since it needs to query the full 75 GB gz-compressed data and the VPS has no superpowers. Download an example (QT interval) here.

Terms and Data Information



        

Terms of use

Feel free to browse around. Upon publication, we will make all data publicly downloadable. Until then, please contact us for more details if you're interested in the underlying data.

Citation in publications

We request that any use of data obtained from the ECGenetics browser cite the ECG Morphology Paper on Biorxiv (https://www.biorxiv.org/content/10.1101/648527v1), please update it to the published version once available here.

Data Generation

A full description of the methods of this project will be provided shortly.

Features

We anticipate features such as:

  • better error handling/stability
  • improved plotting for comparisons (multiple variants/datasets)
  • Mendelian randomization
  • autocomplete
  • export pdf
  • linking different datasets/sites
  • conditional

Contact

‚úČ n.verweij@umcg.nl (Niek Verweij).